Bulletin Samara State Agricultural AcademyBulletin Samara State Agricultural Academy1997-32252782-4225Samara State Agrarian University100727Research ArticleIMMUNE STATUS OF COLOSTRUM DEPENDING ON MILK YIELD AFTER THE FIRST CALVINGBakaevaLarisa N.bakaeva.lora@mail.ruKaramaevaAnna S.annakaramaeva@rambler.ruKaramaevSergey V.karamaevsv@mail.ruOrenburg State Agricultural UniversitySamara State Agrarian University1512202164697514022022Copyright © 2021, Bakaeva L.N., Karamaeva A.S., Karamaev S.V.2021The aim of the research is increasing immune status of dairy breed colostrum by optimizing the value of milk yield after the first calving. For the colostral immunity development and realization of its protective function for newborn calves, it is important that the level of immunoglobulins in the first portion of colostrum is within the physiological range. Research was carried out in the conditions of modern milk production complexes of the Samara, Orenburg regions and the Republic of Bashkortostan. The first colostrum of cows of Black-Motley, Bestuzhev, Holstein and Ayrshire breeds was studied. It was found that value of the first portion of the colostrum, after calving, and milk yield for period of 305 days of lactation have a positive (r = 0.39-0.54) correlation relationship. The maximum yield was shown by cows of the Holstein breed during the third lactation, Black-Motley and Ayrshire breeds the fourth, Bestuzhevskaya - the fifth lactation periods. The study of immunoglobulin dynamics showed that an increase of the single milk yield from 5 to 10 kg leads to a decrease of immunoglobulin content of Black-Motley cows by 35.0 g/l (47.5%), Bestuzhevskaya - by 50.9 g/l (48.1%), Holstein - by 35.2 g/l (51.2%), Ayrshire - by 45.4 g/l (47.5%) breeds. At the same time, on average for each breed, the content of IgG decreases by 2.1-2.3 times, the content of IgA - by 1.83-2.28 g/l (24.5-25.4%), IgM - by 1.06-1.36 g/l (25.4-22.7%). High immune status of the colostrum is preserved by Black-Motley cows after the first calving 5-7 kg, Bestuzhevskaya - 5-9, Holstein - 5-6, Ayrshire - 5-9 kg. This is due to the breed of cows and their characteristic level of immunoglobulins in colostrum.calvescolostrummilk yieldimmunoglobulinscolostral immunityтелятамолозивоудойиммуноглобулиныколостральный иммунитет[Валитов Х. З., Карамаев С. В. Продуктивное долголетие коров в условиях интенсивной технологии молока : монография. Кинель : РИЦ СГСХА, 2012. 325 с.][Донник И. М., Неверова О. П., Горелик О. В. Качество молозива и сохранность телят в условиях использования природных энтеросорбентов // Аграрный вестник Урала. 2016. №7(149). С. 43-52.][Еременко, О. Н. Содержание и кормление телят : монография. Краснодар : КубГАУ, 2012. 96 с.][Карамаев С. В., Карамаева А. С., Соболева Н. В. Технологические свойства молока коров молочных пород в зависимости от сезона отела : монография. Кинель : РИЦ СГСХА, 2016. 181 с.][Карамаев С. В., Бакаева Л. Н., Карамаева А. С., Соболева Н. В. Качество молозива и влияние на него генетических и паратипических факторов : монография. Кинель : РИО СамГАУ, 2020. 185 с.][Молозиво. Иммуноглобулины молозива. Качество и нормы скармливания молозива новорожденным телятам : рекомендации. Гродно : ГГАУ, 2010. 99 с.][Топурия Л. Ю., Карамаев С. В., Порваткин И. В., Топурия Г. М. Лечебно-профилактические свойства пробиотиков при болезнях телят : монография. М. : Перо, 2013. 160 с.][Akers R. M. Major advances associated with hormone and growth factor regulation of mammary growth and lactation in dairy cows. J. Dairy Sci. 2006. 89(4). Р. 1222-1234.][Fallon R. J. Immunoglobulins and the newborn calf. Eds. T. P. Lyons // Biotechnology in the feed industry. Nichlasville : ALL Tech. Technical Publications, 1990. Р. 294-313.][Quigley J. D., Lago A., Chapman C., Erickson P., Polo J. Evalution of the Brix refractometer to estimate immunoglobulin G concentration in bovine colostrums // J. Dairy Sci. 2013. Vol. 96. Р. 1148-1155.]